Posted: December 21st, 2015

Explain how the biochemistry of fungi and pseudo-fungi differs such that certain drugs, such as the azoles, triazoles or enchinocandins, which are very effective in treating various true fungal infections are ineffective in treating pseudo-fungal infections, whilst the polyene class of drug, such as Amp-B, are able to treat both types of infection.

Drugs that target organisms from the kingdom ‘mycota’ may often be ineffective against species of mycota that are in the group ‘pseudo-fungi’. Explain how the biochemistry of fungi and pseudo-fungi differs such that certain drugs, such as the azoles, triazoles or enchinocandins, which are very effective in treating various true fungal infections are ineffective in treating pseudo-fungal infections, whilst the polyene class of drug, such as Amp-B, are able to treat both types of infection.