Posted: December 21st, 2015

Drug X, structure shown below, has a molecular weight of 257, a calculated Log P value of 2.4 and a pKa of 9.5, undergoes hepatic metabolism to yield a variety of Phase I and II metabolites.

Principles of Pharmaceuticals Science

Each question is worth a total of 100 marks.

Question 1:

Describe how physiological adaptations of the gastrointestinal tract allow this organ to fulfil its primary functions.

(100% Marks)

Question 2:

Drug X, structure shown below, has a molecular weight of 257, a calculated Log P value of 2.4 and a pKa of 9.5, undergoes hepatic metabolism to yield a variety of Phase I and II metabolites.