Posted: September 24th, 2015

Blood, Lymphatic System, and Immunity.

submit two (2) case studies dealing with disorders of the blood and/or immune system

Hematology Case Study – Case 1

A 30-year-old developed flulike symptoms with fatigue, afternoon fever, night sweats, weight loss, abdominal cramping, and significant diarrhea. She had taken in very little water over the few days prior to admission the hospital. Blood tests revealed the following:

Hematocrit (Hct): 56%
Leukocytes: 1000/cu mm
Serum potassium: 3.2 mEq/L
CD4 T-cell counts: <200/µl of blood

This individual was treated with antibiotics for infection and rehydrated with fluid containing potassium. The hematocrit reversed itself after the fluid was given and then the individual became anemic.

What is the diagnosis of this individual?
What caused the hematocrit abnormality?
What are leukocytes?
What treatments are available for this disorder?
What is the term for this person’s potassium level prior to treatment
What effect could this abnormal potassium level potentially have on the heart?
What test(s) are used to diagnose this disorder?
What is the incidence and prevalence of this disease in the U.S.?
Hematology Case Study – Case 2

A 62-year-old male complained of weakness, headache, light-headedness, and fatigue. Upon physical examination, the following information was available:

Erythrocytes 8.5 million/cu mm
Leukocytes 12,500/cu mm
Thrombocytes 400,000/cu mm
Hct 58%
O2 saturation (arterial) 94%
Serum erythropoietin Undetectable

The erythrocytes and leukocytes were immature in the peripheral blood smear. The spleen was enlarged. The determined therapy of choice was phlebotomy, 300-500 mL every other day, until the hematocrit was <45% with the possibility of myelosuppressive therapy, if needed.

What is the disorder of this individual?
Why are the arterial O2 saturation and erythropoietin levels important in making this decision?
Define phlebotomy.
How does phlebotomy help correct this problem?
Define myelosuppressive therapy.
Why may myelosuppressive therapy be needed?
What are thrombocytopenia and thrombocytosis?

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